Last update :
28/04/2024
References   References 293  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/50/11/2364

Research teams : Grand Rapids - Butterworth Hospital Pharmacy
Authors : Jones JW, Davis AT.
Title : Stability of bupivacaine hydrochloride in polypropylene syringes.
Reference : Am J Hosp Pharm ; 50: 2364-2365. 1993

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions

List of drugs
InjectionBupivacaine hydrochloride Local anesthetic
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 1,25 mg/ml 23°C Light
32 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 1,25 mg/ml 3°C Protect from light
32 Day

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