Last update :
18/04/2024
InfoStab
Infostab
List of drugs
List of drugs
Summary lists
Summary lists
Search for compatibilities
Search for compatibilities
Y-site compatibility table
Y-site compatibility table
References
References
Research teams
Research teams
Valistab
Valistab
Poster
Poster
Links
Links
Sponsors
Sponsors
Authors
Authors
User’s guide
User’s guide
Newsletter
Newsletter
References   References 2881  
Type : Poster
Icone.pdf
390Ko
Research teams : Créteil - Henri Mondor University Hospital, Department of Pharmacy
Authors : Jaccoulet E, Guirao S, Morand K, Astier A, Paul M.
Title : Stabilité d'un anticorps monoclonal d'intérêt thérapeutique après reconstitution: le rituximab.
Reference : SFPO Congress 2009
Level of Evidence : 
Level of evidence B+
Physical stability : 
Turbidimetry Protein: Dynamic Light Scattering Protein: Size Exclusion Chromatography 
Chemical stability : 
Protein: Peptide mapping
Protein: ionic chromatography
Protein: ultraviolet spectrometry and second derivative
Other methods : 
Comments : 
Protein: no biological methods
List of drugs
InjectionRituximab Anticancer drug
Factors which affect stability Temperature 40°C Induces Degradation
Stability in solutions Polyolefine Sodium chloride 0,9% 1 mg/ml 4°C Protect from light
90 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 4 mg/ml 4°C Protect from light
90 Day
  Mentions Légales