Last update :
19/11/2024
References   References 2827  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/66/19/1722

Research teams : Oslo - The National Hospital (Rikshospitalet), The National Hospital Pharmacy
Authors : Brustugun J, Lao YE, Fagern?s C, Br?nden J, Kristensen S.
Title : Long-term stability of extemporaneously prepared captopril oral liquids in glass bottles
Reference : Am J Health-Syst Pharm ; 66: 1722-1725. 2009

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
Oral solutionCaptopril Antihypertensive
Stability in solutions Glass powder 100 mg
Sorbitol 28.7 g
Sodium edetate 10 mg
Sodium benzoate 100 mg
hydrochloric acid >> pH 3.9
Purified water >> 100 ml
21-23°C Protect from light
365 Day
Stability in solutions Glass powder 500 mg
Sorbitol 28.7 g
Sodium edetate 10 mg
Sodium benzoate 100 mg
hydrochloric acid >> pH 3.9
Purified water >> 100 ml
21-23°C Protect from light
365 Day

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