| Type : |
Journal |
| Web link : |
http://www.ajhp.org/cgi/content/abstract/66/19/1722 |
|
| Research teams : |
Oslo - The National Hospital (Rikshospitalet), The National Hospital Pharmacy |
| Authors : |
Brustugun J, Lao YE, Fagern?s C, Br?nden J, Kristensen S. |
| Title : |
Long-term stability of extemporaneously prepared captopril oral liquids in glass bottles |
| Reference : |
Am J Health-Syst Pharm ; 66: 1722-1725. 2009 |
|
| Level of Evidence : |
|
| Physical stability : |
|
| Chemical stability : |
|
| Other methods : |
|
| Comments : |
|
List of drugs
Captopril
|
 |
 |
 |
 |
100 mg
|
| Sorbitol |
28.7 g |
| Sodium edetate |
10 mg |
| Sodium benzoate |
100 mg |
| hydrochloric acid |
>> pH 3.9 |
| Purified water |
>> 100 ml |
|
21-23°C |
 |
| 365 |
 |
|
|
 |
 |
 |
500 mg
|
| Sorbitol |
28.7 g |
| Sodium edetate |
10 mg |
| Sodium benzoate |
100 mg |
| hydrochloric acid |
>> pH 3.9 |
| Purified water |
>> 100 ml |
|
21-23°C |
 |
| 365 |
 |
|
|
|
|