Last update :
03/05/2024
References   References 2810  
Type : Journal

Research teams : Poitiers - Centre Hospitalier Universitaire de Poitiers
Authors : Dupuis A, Tournier N, Le Moal G, Venisse N.
Title : Preparation and stability of voriconazole eye drop solution.
Reference : Antimicrob Agents Chemother ; 53, 2: 798-799. 2009

Level of Evidence : 
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement Measurement of osmolality 
Comments : 

List of drugs
Eye-dropsVoriconazole Antifungal
Stability in solutions Glass Medicine bottle for injection 200 mg
Vfend®
Water for injection >> 20 ml
2-6°C Protect from light
30 Day
Stability in solutions Glass Medicine bottle for injection 200 mg
Vfend®
Water for injection >> 20 ml
21-27°C With or without light
30 Day

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