Last update :
19/11/2024
References   References 2783  
Type : Journal
Web link : https://doi.org/10.1016/j.ijpharm.2015.04.008

Research teams : Rotterdam - Erasmus MC University Hospital, Department of Pharmacy
Authors : Abdulla A,.van Leeuwen R.W.F, de Vries Schultink A.H.M,.Koch B.C.P.
Title : Stability of colistimethate sodium in a disposable elastomeric infusion device.
Reference : Int J Pharm ; 486; 1-2: 367-369. 2015

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
Degradation products identified and quantified

List of drugs
injectionColistin mesilate sodium Antibiotic
Stability in solutions Silicone elastomer Sodium chloride 0,9% 0,8 mg/ml 4°C Not specified
3 Day

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