Last update :
19/11/2024
References   References 274  
Type : Journal

Research teams : Los Angeles - University of Southern california, School of Pharmacy
Authors : Moon YSK, Chung KC, Chin A, Gill MA.
Title : Stability of piperacillin sodium-tazobactam sodium in polypropylene syringes and polyvinyl chloride minibags.
Reference : Am J Health-Syst Pharm ; 52: 999-1001. 1995

Level of Evidence : 
Level of evidence D
Physical stability : 
Chemical stability : 
Stability defined as 90% of the initial concentration
Other methods : 
Comments : 
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Increased concentration unexplained
No comments for the degradation products

List of drugs
injectionPiperacillin sodium / tazobactam Antibiotic
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 80 / 10 mg/ml -15°C Protect from light
30 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 80 / 10 mg/ml 25°C Not specified
24 Hour
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 80 / 10 mg/ml 4°C Protect from light
7 Day
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 150 / 18,75 mg/ml 4°C Protect from light
7 Day
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 150 / 18.75 mg/ml -15°C Protect from light
30 Day
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 150 / 18.75 mg/ml 25°C Not specified
24 Hour
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 200 / 25 mg/ml -15°C Protect from light
30 Day
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 200 / 25 mg/ml 25°C Not specified
24 Hour
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 200 / 25 mg/ml 4°C Protect from light
7 Day

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