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22/08/2024
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References 26
Type :
Journal
Research teams :
Athens - University of Georgia, College of Pharmacy
Authors :
Stewart JT, Warren FW, King DT, Venkateshwaran TG, Ponder GW, Fox JL.
Title :
Stability of ondansetron hydrochloride, doxorubicin hydrochloride, and dacarbazine or vincristine sulfate in elastomeric portable infusion devices and polyvinyl chloride bags.
Reference :
Am J Health-Syst Pharm ; 54: 915-920. 1997
Level of Evidence :
Physical stability :
Chemical stability :
Other methods :
Comments :
Repeatability / reproducibility / standard range: results not provided or results outside specified values
No comments for the degradation products
Method not shown but the article refers to a validated method
List of drugs
Dacarbazine
Doxorubicin hydrochloride
Ondansetron hydrochloride
Vincristine sulfate
30°C
Ondansetron hydrochloride
0,96 mg/ml
Doxorubicin hydrochloride
0,8 mg/ml
Vincristine sulfate
0,028 mg/ml
5
30°C
Ondansetron hydrochloride
0,64 mg/ml
Dacarbazine
8 mg/ml
Doxorubicin hydrochloride
0,8 mg/ml
24
4°C
Ondansetron hydrochloride
0,64 mg/ml
Dacarbazine
8 mg/ml
Doxorubicin hydrochloride
0,8 mg/ml
7
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