Last update :
19/11/2024
References   References 2547  
Type : Journal
Web link : https://doi.org/10.1345/aph.19026

Research teams : Singapore - Department of Pharmacy, Faculty of Science, National University of Singapore
Authors : Ho PC, Soh H, Lim SM, Yow KL.
Title : Stability of extemporaneously prepared gentamicin ophthalmic solutions.
Reference : Ann Pharmacotherapy ;35:1293-1294. 2001

Level of Evidence : 
Physical stability : 
Chemical stability : 
Stability defined as 90% of the initial concentration
Other methods : 
Measurement of osmolality PH measurement 
Comments : 

List of drugs
Eye-dropsGentamicin sulfate Antibiotic
Factors which affect stability Temperature 25°C Induces Reduced stability
Stability in solutions Glass Medicine bottle for injection 80 mg
®=?
NaCl 0.9% >>10 ml
2-8°C Protect from light
42 Day
Stability in solutions Glass Medicine bottle for injection 140 mg
®=?
NaCl 0.9% >>10 ml
2-8°C Protect from light
42 Day
Stability in solutions Glass Medicine bottle for injection 80 mg
®=?
NaCl 0.9% >>10 ml
26°C Not specified
7 Day
Stability in solutions Glass Medicine bottle for injection 140 mg
®=?
NaCl 0.9% >>10 ml
26°C Not specified
7 Day

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