| Type : |
Journal |
| Web link : |
https://doi.org/10.1177/106002809703101102 |
|
| Research teams : |
Dunedin - University of Otago |
| Authors : |
Fawcett JP, Morgan NC, Woods DJ. |
| Title : |
Formulation and stability of naltrexone oral liquid for rapid withdrawal from methadone.
|
| Reference : |
Ann Pharmacotherapy ;31:1291-1295. 1997 |
|
| Level of Evidence : |
|
| Physical stability : |
|
| Chemical stability : |
|
| Other methods : |
|
| Comments : |
|
List of drugs
 Naltrexone
|
 |
 |
 |
 |
500 mg
Naltrexone |
| Ascorbic acid |
250 mg |
| Sodium saccharin |
50 mg |
| Sodium benzoate |
50 mg |
| Sorbitol |
70% - 20 ml |
| Yellow dye |
0.42 ml |
| Distilled water |
>> 50 ml |
|
25°C |
 |
| 30 |
 |
|
|
|
|
 |
500 mg
Trexan® |
| Ascorbic acid |
250 mg |
| Sodium saccharin |
50 mg |
| Sodium benzoate |
50 mg |
| Sorbitol |
70% - 20 ml |
| Yellow dye |
0.42 ml |
| Distilled water |
>> 50 ml |
|
25°C |
|
| 30 |
|
|
|
|
|
|
500 mg
Naltrexone |
| Ascorbic acid |
250 mg |
| Sodium saccharin |
50 mg |
| Sodium benzoate |
50 mg |
| Sorbitol |
70% - 20 ml |
| Yellow dye |
0.42 ml |
| Distilled water |
>> 50 ml |
|
4°C |
 |
| 30 |
|
|
|
|
|
|
500 mg
Trexan® |
| Ascorbic acid |
250 mg |
| Sodium saccharin |
50 mg |
| Sodium benzoate |
50 mg |
| Sorbitol |
70% - 20 ml |
| Yellow dye |
0.42 ml |
| Distilled water |
>> 50 ml |
|
4°C |
|
| 30 |
|
|
|
|
|
