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References   References 242  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/43/4/917
Research teams : Tucson - University of Arizona, Department of Pharmacy Practice & Science
Authors : Campbell S, Nolan PE, Bliss M, Wood R, Mayersohn M.
Title : Stability of amiodarone hydrochloride in admixtures with other injectable drugs.
Reference : Am J Hosp Pharm ; 43: 917-921. 1986
Level of Evidence : 
Level of evidence C
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
List of drugs
injectionAmiodarone hydrochloride Anti-arrhythmic
Stability in solutions Polyolefine Sodium chloride 0,9% 1,8 mg/ml 24°C Light
24 Hour
Stability in solutions Polyolefine Glucose 5% 1,8 mg/ml 24°C Light
24 Hour
Compatible 1.8 mg/ml + injectionFurosemide 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 1.8 mg/ml + injectionLidocaine hydrochloride 4 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 1.8 mg/ml + injectionPotassium chloride 40 mEq/l + NaCl 0,9% or Glucose 5%
Compatible 1.8 mg/ml + injectionProcainamide hydrochloride 4 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 1.8 mg/ml + injectionQuinidine gluconate 1 mg/ml + Sodium chloride 0,9%
Incompatible 1.8 mg/ml + injectionQuinidine gluconate 1 mg/ml + Glucose 5%
Compatible 1.8 mg/ml + injectionVerapamil hydrochloride 0.05 mg/ml + NaCl 0,9% or Glucose 5%
injectionFurosemide Diuretic
Compatible 0.2 mg/ml + injectionAmiodarone hydrochloride 1.8 mg/ml + NaCl 0,9% or Glucose 5%
injectionLidocaine hydrochloride Local anesthetic
Compatible 4 mg/ml + injectionAmiodarone hydrochloride 1.8 mg/ml + NaCl 0,9% or Glucose 5%
injectionPotassium chloride Electrolyte
Compatible 40 mEq/l + injectionAmiodarone hydrochloride 1.8 mg/ml + NaCl 0,9% or Glucose 5%
injectionProcainamide hydrochloride Anti-arrhythmic
Compatible 4 mg/ml + injectionAmiodarone hydrochloride 1.8 mg/ml + NaCl 0,9% or Glucose 5%
injectionQuinidine gluconate Anti-arrhythmic
Compatible 1 mg/ml + injectionAmiodarone hydrochloride 1.8 mg/ml + Sodium chloride 0,9%
Incompatible 1 mg/ml + injectionAmiodarone hydrochloride 1.8 mg/ml + Glucose 5%
injectionVerapamil hydrochloride Anti-arrhythmic
Compatible 0.05 mg/ml + injectionAmiodarone hydrochloride 1.8 mg/ml + NaCl 0,9% or Glucose 5%
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