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References   References 2396  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/65/5/441
Research teams : Edmonton - University of Alberta, Faculty of Pharmacy and Pharmaceutical Sciences
Authors : Aliabadi HM, Romanick M, Desai S, Lavasanifar A.
Title : Effect of buffer and antioxidant on stability of a mercaptopurine suspension
Reference : Am J Health-Syst Pharm ; 65: 441-447. 2008
Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
List of drugs
Oral solutionMercaptopurine Anticancer drug
Factors which affect stability Storage Light Induces Degradation
Factors which affect stability Temperature 4°C Induces Degradation
Factors which affect stability excipient Induces Enhanced stability
Stability in solutions Glass tablets 500 mg
Purinethol®
Purified water 1,7 ml
Simple syrup 3,3 ml
Cherry syrup >> 10 ml
19-23°C Protect from light
35 Day
Stability in solutions Glass tablets 500 mg
Purinethol®
Ascorbic acid 10 mg
Purified water 1,7 ml
Simple syrup 3,3 ml
Cherry syrup >> 10 ml
19-23°C Protect from light
77 Day
Stability in solutions Glass tablets 500 mg
Purinethol®
NaH2PO4 500 mg
Purified water 1,7 ml
Simple syrup 3,3 ml
Cherry syrup >>> 10 ml
19-23°C Protect from light
28 Day
Stability in solutions Glass tablets 500 mg
Purinethol®
Ascorbic acid 10 mg
Purified water 1,7 ml
NaH2PO4 500 mg
Simple syrup 3,3 ml
Cherry syrup >> 10 ml
19-23°C Protect from light
63 Day
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