Last update :
19/11/2024
References   References 2374  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/47/1/147

Research teams : Columbus - The Ohio State University Hospitals, Department of Pharmacy
Authors : CM Paap CM, Nahata MC.
Title : Stability of cefotaxime in two peritoneal dialysis solutions
Reference : Am J Hosp Pharm ; 47: 147 - 150. 1990

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point

List of drugs
injectionCefotaxime sodium Antibiotic
Stability in solutions Polyvinyl chloride Dianéal® PD1 1.5% glucose (Baxter) 0,86 mg/ml 37°C Not specified
6 Hour
Stability in solutions Polyvinyl chloride Dianéal® PD1 1.5% glucose (Baxter) 0,92 mg/ml 25°C Not specified
24 Hour
Stability in solutions Polyvinyl chloride Dianéal® PD1 4.25% glucose (Baxter) 0,80 mg/ml 37°C Not specified
6 Hour
Stability in solutions Polyvinyl chloride Dianéal® PD1 4.25% glucose (Baxter) 0,87 mg/ml 25°C Not specified
24 Hour

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