Last update :
29/10/2024
References   References 235  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/51/18/2273

Research teams : Los Angeles - University of Southern california, School of Pharmacy
Authors : Choi JS, Burm JP, Jhee SS, Chin A, Ulrich RW, Gill MA.
Title : Stability of piperacillin sodium-tazobactam sodium and ranitidine hydrochloride in 0.9% sodium chloride injection during simulated Y-site administration.
Reference : Am J Hosp Pharm ; 51: 2273-2276. 1994

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Method not shown but the article refers to a validated method

List of drugs
injectionPiperacillin sodium / tazobactam Antibiotic
injectionRanitidine hydrochloride Antihistamine (H2)
Stability of mixtures
Glass Sodium chloride 0,9% 23°C Light
injection Ranitidine hydrochloride 0,5 & 2 mg/ml
injection Piperacillin sodium / tazobactam 80/10 mg/ml
4 Hour

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