Last update :
19/11/2024
References   References 2334  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/66/9/860

Research teams : Rochester - Mayo Clinic, Department of pharmacy
Authors : McCluskey S.V, Graner K.K, Kemp J, Aloumanis V, Ben M, Kupiec T, Nicole Vu N.
Title : Stability of fentanyl 5 µg/mL diluted with 0.9% sodium chloride injection and stored in polypropylene syringes
Reference : Am J Health-Syst Pharm ; 66, 9: 860-863. 2009

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions

List of drugs
injectionFentanyl citrate Analgesic
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 5 µg/ml 23-27°C Protect from light
90 Day

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