Last update :
28/04/2024
References   References 2323  
Type : Journal

Research teams : Mont Godinne - Drug Stability Research Group (DSRG) - CHU UCL NAMUR, site de Godinne
Authors : Galanti L, Lebitasy M.P, Hecq J.D, Cadrobbi J, Vanbeckbergen D, Jamart J.
Title : Long-Term Stability of 5-Fluorouracil in 0.9% Sodium Chloride after Freezing, Microwave Thawing, and Refrigeration
Reference : Can J Hosp Pharm ; 62, 1 2009

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Microscopic examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions

List of drugs
InjectionFluorouracil Anticancer drug
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 8 mg/ml -20°C Protect from light
79 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 8 mg/ml 5°C Protect from light
28 Day

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