Last update :
03/05/2024
References   References 2312  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=2901

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Trissel L.A, Trusley C, Kupiec T.C, Ben M.
Title : Compatibility and stability of palonosetron hydrochloride and propofol during simulated Y-site administration.
Reference : Int J Pharm Compound ; 13, 1: 78-80. 2009

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 

List of drugs
InjectionPalonosetron hydrochloride Antiemetic
Compatible 50 µg/ml + InjectionPropofol 10 mg/ml + None
InjectionPropofol General anesthetic
Compatible 10 mg/ml + InjectionPalonosetron hydrochloride 50 µg/ml + None
Stability of mixtures
Polypropylene None 25°C Light
Injection Palonosetron hydrochloride 25 µg/ml
Injection Propofol 5 mg/ml
4 Hour

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