Last update :
19/11/2024
References   References 2307  
Type : Journal

Research teams : London - Pembridge palliative care unit
Authors : Kreeger L, Cowin P, Noble-Gresty J, Naysmith A.
Title : Epidural diamorphine and bupivacaine stability study.
Reference : Palliative Med ; 9, 4: 315-318. 1995

Level of Evidence : 
Level of evidence B
Physical stability : 
Chemical stability : 
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Method not shown but the article refers to a validated method
No visual inspection

List of drugs
injectionBupivacaine hydrochloride Local anesthetic
injectionDiamorphine hydrochloride Analgesic
Stability of mixtures
Polyvinyl chloride None 25°C Protect from light
injection Bupivacaine hydrochloride 2,5 et 5 mg/ml
injection Diamorphine hydrochloride 0,5 >> 10 mg/ml
8 Day

  Mentions Légales