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References   References 2297  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=2870
Research teams : Ottawa - The Ottawa Hospital, department of Pharmacy
Authors : Donnelly R.F, Corman C.
Title : Physical compatibility and chemical stability of a concentrated solution of atropine sulfate (2 mg/ml) for use as an antidote in nerve agent casualties.
Reference : Int J Pharm Compound ; 11, 6: 550-552 2008
Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
List of drugs
InjectionAtropine sulfate Antimuscarinic
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 2 mg/ml 23°C Light
364 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 2 mg/ml 35°C Light
28 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 2 mg/ml 5°C Protect from light
364 Day
  Mentions Légales