Last update :
18/07/2024
References   References 226  
Type : Journal

Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Walker SE, DeAngelis C, Iazzetta J.
Title : Stability and compatibility of combinations of hydromorphone and a second drug.
Reference : Can J Hosp Pharm ; 44: 289-295. 1991

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAmpicillin sodium Antibiotic
Compatible 20 & 250 mg/ml + injectionHydromorphone hydrochloride 2 >> 40 mg/ml + Glucose 5%
injectionCefazolin sodium Antibiotic
Incompatible >200 mg/ml + injectionHydromorphone hydrochloride 2 >> 40 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionHydromorphone hydrochloride 2 >> 40 mg/ml + Glucose 5%
injectionCeftazidime Antibiotic
Compatible 40 & 180 mg/ml + injectionHydromorphone hydrochloride 2 >> 40 mg/ml + Glucose 5%
injectionCloxacillin sodium Antibiotic
Incompatible 40 & 250 mg/ml + injectionHydromorphone hydrochloride 2 >> 40 mg/ml + Glucose 5%
injectionDiazepam Anxiolytic
Incompatible 5 mg/ml + injectionHydromorphone hydrochloride 2 >> 40 mg/ml + Glucose 5%
injectionHydromorphone hydrochloride Analgesic
Compatible 2 >> 40 mg/ml + injectionAmpicillin sodium 20 & 250 mg/ml + Glucose 5%
Incompatible 2 >> 40 mg/ml + injectionCefazolin sodium >200 mg/ml + Glucose 5%
Compatible 2 >> 40 mg/ml + injectionCefazolin sodium 20 mg/ml + Glucose 5%
Compatible 2 >> 40 mg/ml + injectionCeftazidime 40 & 180 mg/ml + Glucose 5%
Incompatible 2 >> 40 mg/ml + injectionCloxacillin sodium 40 & 250 mg/ml + Glucose 5%
Incompatible 2 >> 40 mg/ml + injectionDiazepam 5 mg/ml + Glucose 5%
Incompatible 2 >> 40 mg/ml + injectionPhenobarbital sodium 120 mg/ml + Glucose 5%
Incompatible 2 >> 40 mg/ml + injectionPhenytoin sodium 50 mg/ml + Glucose 5%
injectionPhenobarbital sodium Antiepileptic
Incompatible 120 mg/ml + injectionHydromorphone hydrochloride 2 >> 40 mg/ml + Glucose 5%
injectionPhenytoin sodium Antiepileptic
Incompatible 50 mg/ml + injectionHydromorphone hydrochloride 2 >> 40 mg/ml + Glucose 5%

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