Last update :
19/11/2024
References   References 224  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/48/3/515

Research teams : Atlanta - Emory University, School of Medecine
Authors : Denson DD, Crews JC, Grummich KW, Stirm EJ, Sue CA.
Title : Stability of methadone hydrochloride in 0.9% sodium chloride injection in single-dose plastic containers.
Reference : Am J Hosp Pharm ; 48: 515-517. 1991

Level of Evidence : 
Level of evidence D
Physical stability : 
Chemical stability : 
Gas chromatography
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point
No visual inspection

List of drugs
injectionMethadone hydrochloride Analgesic
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 1 & 2 & 5 mg/ml 25°C Light
28 Day

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