Last update :
19/11/2024
References   References 2210  
Type : Journal
Web link : http://dx.doi.org/10.4212/cjhp.v60i4.184

Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Walker S.E, Charbonneau F, Law S.
Title : Stability of Docetaxel Solution after Dilution in Ethanol and Storage in Vials and after Dilution in Normal Saline and Storage in Bags.
Reference : Can J Hosp Pharm ; 60, 4: 231-237. 2007

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions

List of drugs
injectionDocetaxel Anticancer drug
Stability in solutions Glass None 10 mg/ml 23°C Light
21 Day
Stability in solutions Glass None 10 mg/ml 4°C Protect from light
21 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 0.4 & 0.8 mg/ml 23°C Light
35 Day

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