Last update :
27/11/2025
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References   References 2130  
Type : Journal
Web link : https://www.jle.com/en/revues/bdc/e-docs/stabilite_du_melange_5_fluoro_uracile_acide_folinique_influence_des_concentrations_du_contenant_et_de_la_forme_de_lacide_folinique_70338/article.phtml
Research teams : Saint-Cloud - Centre René Huguenin, Service de pharmacologie clinique
Authors : Lokiec F, Amirault P, Bonnans H, Gauzan MF, Sauvage N, Santoni J.
Title : Stabilité du mélange 5-fluoro-uracil-acide fonique : influence des concentrations, du contenant et de la forme de l’acide folinique.
Reference : Bull Cancer ; 86, 11: 946-954. 1999
Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only
List of drugs
injectionFluorouracil Anticancer drug
Incompatible 50 mg/ml + injectionFolinate calcium 30.8 mg/ml
Compatible 6.5 mg/ml + injectionFolinate calcium 30.8 mg/ml
Incompatible 50 mg/ml + injectionLevofolinate calcium 15.4 mg/ml
Compatible 6.5 mg/ml + injectionLevofolinate calcium 15.4 mg/ml
injectionFolinate calcium Cytoprotective
Incompatible 30.8 mg/ml + injectionFluorouracil 50 mg/ml
Compatible 30.8 mg/ml + injectionFluorouracil 6.5 mg/ml
injectionLevofolinate calcium Cytoprotective
Incompatible 15.4 mg/ml + injectionFluorouracil 50 mg/ml
Compatible 15.4 mg/ml + injectionFluorouracil 6.5 mg/ml
  Mentions Légales