Last update :
19/11/2024
References   References 2057  
Type : Journal

Research teams : Stevenage - Lister Hospital, Quality Control Laboratory
Authors : Droste JC, Jeraj HA, MacDonald A, Farrington K.
Title : Stability and in vitro efficacy of antibiotic-heparin lock solutions potentially useful for treatment of central venous catheter-related sepsis.
Reference : J Antimicrob Chemother ; 51: 849-855. 2003

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionCiprofloxacin lactate Antibiotic
Incompatible 0.4 & 0.6 mg/ml + injectionHeparin sodium 10 >> 1000 UI/ml + Sodium chloride 0,9%
Incompatible 0.8 mg/ml + injectionHeparin sodium 10 >> 5000 UI/ml + Sodium chloride 0,9%
Incompatible 1 mg/ml + injectionHeparin sodium 10 >> 10000 UI/ml + Sodium chloride 0,9%
Compatible 0.8 mg/ml + injectionHeparin sodium 10000 UI/ml + Sodium chloride 0,9%
Compatible 0.4 & 0.6 mg/ml + injectionHeparin sodium 5000 & 10000 UI/ml + Sodium chloride 0,9%
Compatible 0.2 mg/ml + injectionHeparin sodium 1000 >> 10000 UI/ml + Sodium chloride 0,9%
Compatible 0.1 mg/ml + injectionHeparin sodium 10 >> 10000 UI/ml + Sodium chloride 0,9%
Incompatible 0.2 mg/ml + injectionHeparin sodium 10 & 100 UI/ml + Sodium chloride 0,9%
injectionHeparin sodium Anticoagulant
Incompatible 10 >> 1000 UI/ml + injectionCiprofloxacin lactate 0.4 & 0.6 mg/ml + Sodium chloride 0,9%
Incompatible 10 >> 5000 UI/ml + injectionCiprofloxacin lactate 0.8 mg/ml + Sodium chloride 0,9%
Incompatible 10 >> 10000 UI/ml + injectionCiprofloxacin lactate 1 mg/ml + Sodium chloride 0,9%
Compatible 10000 UI/ml + injectionCiprofloxacin lactate 0.8 mg/ml + Sodium chloride 0,9%
Compatible 5000 & 10000 UI/ml + injectionCiprofloxacin lactate 0.4 & 0.6 mg/ml + Sodium chloride 0,9%
Compatible 1000 >> 10000 UI/ml + injectionCiprofloxacin lactate 0.2 mg/ml + Sodium chloride 0,9%
Compatible 10 >> 10000 UI/ml + injectionCiprofloxacin lactate 0.1 mg/ml + Sodium chloride 0,9%
Incompatible 10 & 100 UI/ml + injectionCiprofloxacin lactate 0.2 mg/ml + Sodium chloride 0,9%
Compatible 10 >> 10000 UI/ml + injectionLinezolid 0.2 >> 1.92 mg/ml + Sodium chloride 0,9%
Compatible 10 >> 10000 UI/ml + injectionTeicoplanine 0.02 >> 10 mg/ml + Sodium chloride 0,9%
injectionLinezolid Antibiotic
Compatible 0.2 >> 1.92 mg/ml + injectionHeparin sodium 10 >> 10000 UI/ml + Sodium chloride 0,9%
injectionTeicoplanine Antibiotic
Compatible 0.02 >> 10 mg/ml + injectionHeparin sodium 10 >> 10000 UI/ml + Sodium chloride 0,9%

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