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References   References 2056  
Type : Journal
Research teams : Christchurch - Christchurh Hospital, Department of Clinical Pharmacology
Authors : Vella-Brincat JWA, Begg EJ, Gallagher K, kirkpatrick CMJ, Zhang M, Frampton C, Chambers ST.
Title : Stability of benzylpenicillin during continuous home intravenous therapy.
Reference : J Antimicrob Chemother ; 53: 675-677. 2004
Level of Evidence : 
Level of evidence D
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
No visual inspection
List of drugs
InjectionPenicillin G sodium Antibiotic
Factors which affect stability Temperature Increase Induces Degradation
Stability in solutions Not specified Sodium chloride 0,9% 0,13 MUI/ml 21°C-22°C Not specified
13 Hour
Stability in solutions Not specified Sodium chloride 0,9% 0,13 MUI/ml 26°C Not specified
12 Hour
Stability in solutions Not specified Sodium chloride 0,9% 0,13 MUI/ml 3-5°C Not specified
6 Day
Stability in solutions Not specified Sodium chloride 0,9% 0,13 MUI/ml 36°C Not specified
5 Hour
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