Last update :
03/05/2024
References   References 2026  
Type : Journal
Web link : https://doi.org/10.1016/j.jpba.2005.03.013

Research teams : Stockport - Stepping Hill Hospital, Quality Control North Wes
Authors : Rigge D, Jones MF.
Title : Shelf lives of aseptically prepared medicines - stability of piperacillin/tazobactam in PVC and non-PVC bags.
Reference : J Pharm Biomed Anal ; 39: 339-343. 2005

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionPiperacillin sodium / tazobactam Antibiotic
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 40 / 5 mg/ml 25°C Light
4 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 40 / 5 mg/ml 7°C Protect from light
5 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 40 / 5 mg/ml 25°C Light
3 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 40 / 5 mg/ml 7°C Protect from light
17 Day

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