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References   References 1899  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=1799
Research teams : Houston - M.D.Anderson Cancer Center
Authors : Trissel LA, Zhang Y.
Title : Long-term stability of Trimix : a three drug injection used to treat rectile dysfunction.
Reference : Int J Pharm Compound ; 8, 3: 231-235. 2004
Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
List of drugs
injectionAlprostadil Vasodilator
injectionPapaverine hydrochloride Vasodilator
injectionPhentolamine mesylate Vasodilator
Stability of mixtures
Glass NaCl 0,9% + antibacterial -20°C Protect from light
injection Alprostadil 12,5 µg/ml
injection Papaverine hydrochloride 4,5 mg/ml
injection Phentolamine mesylate 0,125 mg/ml
180 Day
Glass NaCl 0,9% + antibacterial 4°C Protect from light
injection Alprostadil 12,5 µg/ml
injection Papaverine hydrochloride 4,5 mg/ml
injection Phentolamine mesylate 0,125 mg/ml
30 Day
  Mentions Légales