Last update :
21/05/2025
References   References 1879  
Type : Journal
Web link : https://pubmed.ncbi.nlm.nih.gov/11587115/

Research teams : Minneapolis - Medtronic, Inc
Authors : Hildebrand KR, Elsberry DE, Deer TR.
Title : Stability, compatibility, and safety of intrathecal bupivacaine administered via an implantable delivery system.
Reference : Clin J Pain : 17: 239-244. 2001

Level of Evidence : 
Level of evidence D
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
No visual inspection
Stability indicating capability inadequately assessed

List of drugs
injectionBupivacaine hydrochloride Local anesthetic
Stability in solutions Not specified None 7,5 mg/ml 37°C Protect from light
84 Day

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