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References   References 1865  
Type : Journal
Research teams : Clermont-Ferrand - University Hospital Gabriel Monpied, Department of Pharmacy
Authors : Sautou-Miranda V, Brigas F, Vanheerswinghels S, Chopineau J.
Title : Compatibility of paclitaxel in 5% glucose solution with ECOFLAC® low-density polyethylene containers - Stability under different storage conditions.
Reference : Int J Pharm ; 178: 77-82. 1999
Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Search of DEHP 
Comments : 
Degradation products not observed in real conditions
List of drugs
InjectionPaclitaxel Anticancer drug
Stability in solutions Glass Glucose 5% 0,4 & 1,2 mg/ml 20°C-25°C Light
5 Day
Stability in solutions Polyethylene Glucose 5% 0,4 & 1,2 mg/ml 20°C-25°C With or without light
5 Day
Stability in solutions Polyethylene Glucose 5% 0,4 & 1,2 mg/ml 4°C Protect from light
5 Day
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