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References   References 183  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/49/9/2223
Research teams : Charleston - Medical University of South Carolina
Authors : Bosso JA, Prince RA, Fox JL.
Title : Stability of ondansetron hydrochloride in injectable solutions at -20, 5, and 25°C.
Reference : Am J Hosp Pharm ; 49: 2223-2225. 1992
Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point
List of drugs
injectionOndansetron hydrochloride Antiemetic
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,03 & 0,3 mg/ml -20°C Protect from light
90 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,03 & 0,3 mg/ml 25°C Light
48 Hour
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,03 & 0,3 mg/ml 4°C Protect from light
14 Day
  Mentions Légales