Last update :
29/10/2024
References   References 1812  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=516

Research teams : Columbia - University of South Carolina, College of Pharmacy
Authors : Fuhrman LC, Godwin DA, Davis RA.
Title : Stability of 5-fluorouracil in an extemporaneously compounded ophtalmic solution.
Reference : Int J Pharm Compound ; 4, 4: 320-323. 2000

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
No comments for the degradation products

List of drugs
injectionFluorouracil Anticancer drug
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0,1 mg/ml -10°C Protect from light
7 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0,1 mg/ml 25°C Light
7 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0,1 mg/ml 40°C Protect from light
7 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0,1 mg/ml 5°C Protect from light
7 Day

  Mentions Légales