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References   References 1762  
Type : Journal
Web link : https://doi.org/10.1016/S0731-7085(98)00096-X
Research teams : Lille - Faculté des Sciences Pharmaceutiques et Biologiques
Authors : Dine T, Khalfi F, Gressier B, Luyckx M, Brunet C, Ballester L, Goudaliez F, Kablan J, Cazin M, Cazin JC.
Title : Stability study of fotemustine in PVC infusion bags and sets under various conditions using a stability-indicating high-performance liquid chromatographic assay.
Reference : J Pharm Biomed Anal ; 18: 373-381. 1998
Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
PH measurement Search of DEHP 
Comments : 
Degradation products not observed in real conditions
List of drugs
injectionFotemustine Anticancer drug
Stability in solutions Polyvinyl chloride Glucose 5% 0,8 & 2 mg/ml 22°C Protect from light
8 Hour
Stability in solutions Polyvinyl chloride Glucose 5% 0,8 & 2 mg/ml 4°C Protect from light
48 Hour
  Mentions Légales