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References   References 1746  
Type : Journal
Web link : http://archive.eahp.eu/Media/Home-page/EJHP-BMJ/EJHP-Practice-archive/Issue-1-2010
Research teams : Lille - Faculté des Sciences Pharmaceutiques et Biologiques
Authors : Kambia N, Merite N, Dine T, Dupin-Spriet T, Gressier B, Luyckx M, Watinne C, Brunet C.
Title : Stability studies of amoxicillin/clavulanic acid combinaison in polyolefin infusion bags.
Reference : EJHP ; 16, 30-37. 2010
Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 
List of drugs
injectionAmoxicillin sodium / clavulanic acid Antibiotic
Stability in solutions Polyolefine Sodium chloride 0,9% 20 / 2 mg/ml 20-25°C Light
4 Hour
Stability in solutions Polyolefine Sodium chloride 0,9% 20 / 2 mg/ml 4°C Protect from light
8 Hour
Stability in solutions Polyolefine Sodium chloride 0,9% 20 / 4 mg/ml 20-25°C Light
4 Hour
Stability in solutions Polyolefine Sodium chloride 0,9% 20 / 4 mg/ml 4°C Protect from light
8 Hour
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