Last update :
19/11/2024
References   References 1728  
Type : Journal

Research teams : Budapest - Central Research Institute for chemistry of the Hungarian Academy of Sciences,
Authors : Mittner A, Vincze Z, Jemnitz.
Title : Stability of cyclophosphamide containing infusions.
Reference : Pharmazie ; 54: 224-225. 1999

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 
No comments for the degradation products

List of drugs
injectionCyclophosphamide Anticancer drug
Stability in solutions Glass Water for Injection 20 mg/ml 24-27°C Not specified
4 Day
Stability in solutions Glass Water for Injection 20 mg/ml 5°C Protect from light
14 Day
Stability in solutions Glass Sodium chloride 0,9% 0,4 mg/ml 2-8°C Protect from light
14 Day
Stability in solutions Glass Sodium chloride 0,9% 0,4 mg/ml 21-25°C Not specified
6 Day

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