Last update :
19/11/2024
References   References 1726  
Type : Journal

Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Turnbull K, Bielech M, Walker SE, Law S.
Title : Stability of oxycodone hydrochloride for injection in dextrose and saline solutions.
Reference : Can J Hosp Pharm ; 55: 272-277. 2002

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions

List of drugs
injectionOxycodone hydrochloride Analgesic
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 5 & 50 mg/ml 24°C Light
35 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 5 & 50 mg/ml 4°C Protect from light
35 Day
Stability in solutions Polypropylen Syringe Water for Injection 100 mg/ml 24°C Light
35 Day
Stability in solutions Polypropylen Syringe Water for Injection 100 mg/ml 4°C Protect from light
35 Day

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