Last update :
19/11/2024
References   References 1706  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=351

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Trissel LA, Xu QA.
Title : Physical and chemical stability of hydromorphone hydrochloride 1.5 and 80 mg/ml packaged in plastic syringes.
Reference : Int J Pharm Compound ; 6: 74-76. 2002

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Turbidimetry Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 

List of drugs
injectionHydromorphone hydrochloride Analgesic
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 1,5 & 80 mg/ml 23°C Light
60 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 1,5 & 80 mg/ml 37°C Protect from light
48 Hour
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 1,5 & 80 mg/ml 4°C Protect from light
60 Day

  Mentions Légales