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References   References 1664  
Type : Journal
Research teams : Athens - University of Georgia, College of Pharmacy
Authors : King AD, Stewart JT, Warren FW.
Title : Stability of cefmetazole-doxycycline mixtures in sodium chloride and dextrose injections.
Reference : J Clin Pharm Ther ; 19: 317-325. 1994
Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 90% of the initial concentration
Other methods : 
Comments : 
List of drugs
injectionCefmetazole sodium Antibiotic
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 4 & 20 mg/ml 4°C Not specified
7 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 4 & 20 mg/ml 23°C Not specified
48 Hour
Stability in solutions Polyvinyl chloride Glucose 5% 4 & 20 mg/ml 23°C Not specified
24 Hour
injectionDoxycycline hyclate Antibiotic
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,8 & 1 mg/ml 23°C Not specified
96 Hour
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,8 & 1 mg/ml 4°C Not specified
7 Day
  Mentions Légales