Last update :
19/11/2024
References   References 166  
Type : Journal

Research teams : Poitiers - Université de Poitiers, Faculté de Médecine et Pharmacie
Authors : Rochard E, Barthes D, Courtois P.
Title : Stability and compatibility study of carboplatin with three portable infusion pump reservoirs.
Reference : Int J Pharm ; 101: 257-262. 1994

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions

List of drugs
injectionCarboplatin Anticancer drug
Stability in solutions Polyvinyl chloride Glucose 5% 1 mg/ml 22°C Protect from light
28 Day
Stability in solutions Polyvinyl chloride Glucose 5% 1 mg/ml 35°C Protect from light
28 Day
Stability in solutions Polyvinyl chloride Glucose 5% 1 mg/ml 4°C Protect from light
28 Day
Stability in solutions Ethylene vinyl acetate Glucose 5% 1 mg/ml 22°C Protect from light
28 Day
Stability in solutions Ethylene vinyl acetate Glucose 5% 1 mg/ml 35°C Protect from light
28 Day
Stability in solutions Ethylene vinyl acetate Glucose 5% 1 mg/ml 4°C Protect from light
28 Day
Stability in solutions Polyisoprene elastomer Glucose 5% 1 mg/ml 22°C Protect from light
28 Day
Stability in solutions Polyisoprene elastomer Glucose 5% 1 mg/ml 35°C Protect from light
28 Day
Stability in solutions Polyisoprene elastomer Glucose 5% 1 mg/ml 4°C Protect from light
28 Day

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