Last update :
28/04/2024
References   References 1648  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=1460

Research teams : Mont Godinne - Drug Stability Research Group (DSRG) - CHU UCL NAMUR, site de Godinne
Authors : Schlesser V, Hecq J-D, Vanbeckbergen D, Jamart J, Galanti LM.
Title : Effect of freezing, long-term storage, and microwave thawing on the stability of cefepime in 5% dextrose infusion polyvinyl chloride bags.
Reference : Int J Pharm Compound ; 6: 391-394. 2002

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions

List of drugs
InjectionCefepime dihydrochloride Antibiotic
Stability in solutions Polyvinyl chloride Glucose 5% 20 mg/ml -20°C Protect from light
30 Day
Stability in solutions Polyvinyl chloride Glucose 5% 20 mg/ml 4°C Protect from light
11 Day

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