Last update :
19/11/2024
References   References 1602  
Type : Journal
Web link : http://www.factsandcomparisons.com/HospitalPharm/?id=63

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Trissel LA, Zhang Y, Cohen MR.
Title : The stablity of diluted vincristine sulfate used as a deterrent to inadvertent intrathecal injection.
Reference : Hosp Pharm ; 36: 740-745. 2001

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
No comments for the degradation products

List of drugs
injectionVincristine sulfate Anticancer drug
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,01>>0,12 mg/ml 4°C Protect from light
7 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0,025>>0,15 mg/ml 4°C Protect from light
7 Day

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