Last update :
29/10/2024
References   References 1505  
Type : Journal
Web link : http://www.eahponline.org/asp/practice_overview_archive.asp?m=4&s=1&year=1997&nr=4&categoryID=61

Research teams : Nancy - University Hospital of Nancy, Department of Pharmacy
Authors : Daouphars M, Vigneron J, Perrin A, Hoffman MA, Hoffman M.
Title : Stability of cladribine in either polyethylene containers or polyvinylchloride bags.
Reference : Eur Hosp Pharm 3,4: 154-6 1997

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
Degradation products not observed in real conditions

List of drugs
injectionCladribine Anticancer drug
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,016 mg/ml 18°C With or without light
30 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,016 mg/ml 4°C Protect from light
30 Day
Stability in solutions Polyethylene Sodium chloride 0,9% 0,016 mg/ml 18°C With or without light
30 Day
Stability in solutions Polyethylene Sodium chloride 0,9% 0,016 mg/ml 4°C Protect from light
30 Day

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