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References   References 144  
Type : Journal
Research teams : Lille - Faculté des Sciences Pharmaceutiques et Biologiques
Authors : Dine T, Luyckx M, Cazin JC, Goudaliez F, Mallevais ML.
Title : Stability and compatibility studies of vinblastine, vincristine, vindesine and vinorelbine with PVC infusion bags.
Reference : Int J Pharm ; 77: 279-285. 1991
Level of Evidence : 
Level of evidence D
Physical stability : 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
Comments : 
Stability indicating capability inadequately assessed
Imperfect separation of the internal standard from the product under study or its degradation products, or understudied
No comments for the degradation products
List of drugs
injectionVinblastine sulfate Anticancer drug
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 mg/ml 4°C Protect from light
7 Day
injectionVincristine sulfate Anticancer drug
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,02 mg/ml 4°C Protect from light
7 Day
injectionVindesine sulfate Anticancer drug
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,02 mg/ml 4°C Protect from light
7 Day
injectionVinorelbine tartrate Anticancer drug
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,5 mg/ml 4°C Protect from light
3 Day
Stability in solutions Polyvinyl chloride Glucose 5% 0,5 mg/ml 4°C Protect from light
7 Day
  Mentions Légales