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References   References 1422  
Type : Journal
Research teams : Houston - M.D.Anderson Cancer Center
Authors : Xu QA, Zhang Y, Trissel LA.
Title : Physical and chemical stability of gemcitabine hydrochloride solutions.
Reference : J Am Pharm Assoc ; 39: 509-513. 1999
Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Turbidimetry Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
List of drugs
injectionGemcitabine hydrochloride Anticancer drug
Stability in solutions Glass Water for Injection 38 mg/ml 23°C With or without light
35 Day
Stability in solutions Glass Sodium chloride 0,9% 38 mg/ml 23°C With or without light
35 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 & 10 mg/ml 23°C With or without light
35 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 & 10 mg/ml 4°C Protect from light
35 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 & 10 & 38 mg/ml 32°C Protect from light
7 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 38 mg/ml 23°C With or without light
35 Day
  Mentions Légales