Last update :
29/10/2024
References   References 1317  
Type : Journal

Research teams : Torquay - Torbay Hospital, Regional Quality Control Laboratory
Authors : Adams PS, Haines-Hutt RF, Bradford E, Palmer A, Rowland CG.
Title : Pharmaceutical aspects of home infusion therapy for cancer patients.
Reference : Pharm J ; 238: 476-478. 1987

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
Stability indicating capability inadequately assessed
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point

List of drugs
injectionEpirubicin hydrochloride Anticancer drug
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0,5 mg/ml 20°C Not specified
28 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0,5 mg/ml 4°C Protect from light
28 Day
injectionIfosfamide Anticancer drug
injectionMesna Cytoprotective
injectionMitoxantrone dihydrochloride Anticancer drug
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0,2 mg/ml 20°C Not specified
28 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0,2 mg/ml 4°C Protect from light
28 Day
Stability of mixtures
Polypropylen Syringe Sodium chloride 0,9% 4°C Protect from light
injection Mesna 40 mg/ml
injection Ifosfamide 50 mg/ml
28 Day
Polypropylen Syringe Sodium chloride 0,9% 4°C Protect from light
injection Epirubicin hydrochloride 1 mg/ml
injection Ifosfamide 50 mg/ml
28 Day

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