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References   References 1274  
Type : Journal
Research teams : Mainz - University Medical Center, Johannes Gutenberg
Authors : Krämer I, Thiesen J.
Title : Pharmazeutische aspekte von topotecan-infusionen.
Reference : TAP Pharmazeutische Zeitung ; 31: 30-33. 1997
Level of Evidence : 
Level of evidence D
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Method not shown but used to deposit authorization to market
List of drugs
injectionTopotecan Anticancer drug
Stability in solutions Glass Water for Injection 1 mg/ml 25°C Not specified
28 Day
Stability in solutions Glass Water for Injection 1 mg/ml 4°C Protect from light
28 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,05 & 0,025 mg/ml 25°C Protect from light
28 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,05 & 0,025 mg/ml 4°C Protect from light
28 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,01 mg/ml 25°C Light
7 Day
Stability in solutions Polyisoprene elastomer NaCl 0,9% or Glucose 5% 0,01 & 0,05 mg/ml 25°C Protect from light
21 Day
Stability in solutions Polyisoprene elastomer NaCl 0,9% or Glucose 5% 0,01 & 0,05 mg/ml 4°C Protect from light
21 Day
  Mentions Légales