Last update :
27/11/2024
References   References 1264  
Type : Journal

Research teams : La Chaussée Saint Victor - Laboratoires Chaix et du Marais
Authors : Truelle-Hugon B, Tourette G, Couineaux B, Gache-Charrette C.
Title : Study of Lavoisier morphine chlorhydrate in different active perfusion systems after reconstitution in different solvents.
Reference : Ann Pharm Fr ; 55: 216-223. 1997

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Water loss by evaporation PH measurement 
Comments : 
Degradation products identified and quantified

List of drugs
injectionMorphine hydrochloride Analgesic
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 mg/ml 37°C Protect from light
14 Day
Stability in solutions Polyvinyl chloride None 20 mg/ml 37°C Protect from light
14 Day
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 1 mg/ml 37°C Protect from light
2 Day
Stability in solutions Polypropylen Syringe None 20 mg/ml 37°C Protect from light
2 Day

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