Last update :
19/11/2024
References   References 126  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/53/21/2606

Research teams : St Lucia - University of Queensland, Department of Pharmacy
Authors : Prankerd RJ, Jones RD.
Title : Physicochemical compatibility of propofol with thiopental sodium.
Reference : Am J Health-Syst Pharm ; 53: 2606-2610. 1996

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Microscopic examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values

List of drugs
injectionPropofol General anesthetic
Compatible 2.5 >> 7.5 mg/ml + injectionThiopental sodium 6.25 >> 18.75 mg/ml + None
injectionThiopental sodium General anesthetic
Compatible 6.25 >> 18.75 mg/ml + injectionPropofol 2.5 >> 7.5 mg/ml + None
Stability of mixtures
Glass None 25°C Not specified
injection Thiopental sodium 12,5 mg/ml
injection Propofol 5 mg/ml
6 Hour

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