Last update :
18/07/2024
References   References 1200  
Type : Journal

Research teams : Bloomfield - Schering-Plough Corporation
Authors : Chaudry IA, Bruey KP, Hurlburt LE, Oden EM.
Title : Compatibility of netilmycin sulfate injection with commonly used intravenous injections and additives.
Reference : Am J Hosp Pharm ; 38: 1737-1742. 1981

Level of Evidence : 
Biological analysis
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement Measurement of osmolality 
Comments : 
No comments for the degradation products

List of drugs
injectionAminocaproic acid Anti-bleeding
Compatible 10 mg/ml + injectionNetilmicin sulfate 3 mg/ml + NaCl 0,9% or Glucose 5%
injectionAtropine sulfate Antimuscarinic
Compatible 0.04 mg/ml + injectionNetilmicin sulfate 3 mg/ml + NaCl 0,9% or Glucose 5%
injectionChlorpromazine hydrochloride Anxiolytic
Compatible 0.1 mg/ml + injectionNetilmicin sulfate 3 mg/ml + NaCl 0,9% or Glucose 5%
injectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 0.08 mg/ml + injectionNetilmicin sulfate 3 mg/ml + NaCl 0,9% or Glucose 5%
injectionDiazepam Anxiolytic
Compatible 0.04 mg/ml + injectionNetilmicin sulfate 3 mg/ml + NaCl 0,9% or Glucose 5%
injectionDiphenhydramine hydrochloride Antihistamine (H1)
Compatible 0.4 mg/ml + injectionNetilmicin sulfate 3 mg/ml + NaCl 0,9% or Glucose 5%
injectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 0.8 mg/ml + injectionNetilmicin sulfate 3 mg/ml + NaCl 0,9% or Glucose 5%
injectionIron dextran Various
Compatible + injectionNetilmicin sulfate 3 mg/ml + NaCl 0,9% or Glucose 5%
injectionIsoprenaline hydrochloride Beta-stimulant
Compatible 0.4 mg/ml + injectionNetilmicin sulfate 3 mg/ml + NaCl 0,9% or Glucose 5%
injectionNeostigmine methylsulfate Various
Compatible 0.04 mg/ml + injectionNetilmicin sulfate 3 mg/ml + NaCl 0,9% or Glucose 5%
injectionNetilmicin sulfate Antibiotic
Stability in solutions Glass Water for Injection 3 mg/ml 25°C Not specified
7 Day
Stability in solutions Glass Water for Injection 3 mg/ml 4°C Protect from light
7 Day
Stability in solutions Glass NaCl 0,9% or Glucose 5% 3 mg/ml 25°C Not specified
7 Day
Stability in solutions Glass NaCl 0,9% or Glucose 5% 3 mg/ml 4°C Protect from light
7 Day
Stability in solutions Glass Ringer’s lactate solution 3 mg/ml 25°C Not specified
7 Day
Stability in solutions Glass Ringer’s lactate solution 3 mg/ml 4°C Protect from light
7 Day
Stability in solutions Glass Sodium chloride 3% 3 mg/ml 25°C Not specified
7 Day
Stability in solutions Glass Sodium chloride 3% 3 mg/ml 4°C Protect from light
7 Day
Stability in solutions Glass Glucose 10% 3 mg/ml 25°C Not specified
7 Day
Stability in solutions Glass Glucose 10% 3 mg/ml 4°C Protect from light
7 Day
Compatible 3 mg/ml + NaHCO3
Compatible 3 mg/ml + injectionAminocaproic acid 10 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 3 mg/ml + injectionAtropine sulfate 0.04 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 3 mg/ml + injectionChlorpromazine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 3 mg/ml + injectionDexamethasone sodium phosphate 0.08 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 3 mg/ml + injectionDiazepam 0.04 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 3 mg/ml + injectionDiphenhydramine hydrochloride 0.4 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 3 mg/ml + injectionHydrocortisone sodium succinate 0.8 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 3 mg/ml + injectionIron dextran + NaCl 0,9% or Glucose 5%
Compatible 3 mg/ml + injectionIsoprenaline hydrochloride 0.4 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 3 mg/ml + injectionNeostigmine methylsulfate 0.04 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 3 mg/ml + injectionNorepinephrine bitartrate 0.064 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 3 mg/ml + injectionOxytocin + NaCl 0,9% or Glucose 5%
Compatible 3 mg/ml + injectionPhytomenadione 0.1 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 3 mg/ml + injectionPotassium chloride + NaCl 0,9% or Glucose 5%
Compatible 3 mg/ml + injectionProcainamide hydrochloride 4 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 3 mg/ml + injectionPromethazine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 3 mg/ml + injectionTriflupromazine hydrochloride 0.4 mg/ml + NaCl 0,9% or Glucose 5%
injectionNorepinephrine bitartrate Sympathomimetic
Compatible 0.064 mg/ml + injectionNetilmicin sulfate 3 mg/ml + NaCl 0,9% or Glucose 5%
injectionOxytocin Various
Compatible + injectionNetilmicin sulfate 3 mg/ml + NaCl 0,9% or Glucose 5%
injectionPhytomenadione Vitamin
Compatible 0.1 mg/ml + injectionNetilmicin sulfate 3 mg/ml + NaCl 0,9% or Glucose 5%
injectionPotassium chloride Electrolyte
Compatible + injectionNetilmicin sulfate 3 mg/ml + NaCl 0,9% or Glucose 5%
injectionProcainamide hydrochloride Anti-arrhythmic
Compatible 4 mg/ml + injectionNetilmicin sulfate 3 mg/ml + NaCl 0,9% or Glucose 5%
injectionPromethazine hydrochloride Antihistamine (H1)
Compatible 0.1 mg/ml + injectionNetilmicin sulfate 3 mg/ml + NaCl 0,9% or Glucose 5%
injectionTriflupromazine hydrochloride Neuroleptic
Compatible 0.4 mg/ml + injectionNetilmicin sulfate 3 mg/ml + NaCl 0,9% or Glucose 5%

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