Last update :
29/10/2024
References   References 1071  
Type : Journal

Research teams : West Point - Merck and Co
Authors : Bergquist PA, Zimmermann J, Kenney RR, Han RYH, Hunke WA.
Title : Stability of tirofiban hydrochloride in three commonly used IV solutions and polyvinyl chloride administration sets.
Reference : Am J Health-Syst Pharm ; 56: 1627-1629. 1999

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions

List of drugs
injectionTirofiban Anticoagulant
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 50 µg/ml 20°C-25°C Light
24 Hour
Stability in solutions Polyvinyl chloride NaCl 0,45% Glucose 5% 50 µg/ml 20°C-25°C Light
24 Hour

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