Last update :
28/04/2024
References   References 1068  
Type : Journal

Research teams : Athens - University of Georgia, College of Pharmacy
Authors : Stewart JT, Warren FW, Maddox FC.
Title : Stability of cefepime hydrochloride in polypropylene syringes at -20°C, 4°C and 22-24°C.
Reference : Am J Health-Syst Pharm ; 56: 457-459. 1999

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionCefepime dihydrochloride Antibiotic
Stability in solutions Polypropylen Syringe Water for Injection 100 & 200 mg/ml -20°C Protect from light
90 Day
Stability in solutions Polypropylen Syringe Water for Injection 100 & 200 mg/ml 4°C Protect from light
7 Day
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 100 & 200 mg/ml -20°C Protect from light
90 Day
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 100 & 200 mg/ml 4°C Protect from light
7 Day

  Mentions Légales