Last update :
28/04/2024
References   References 1040  
Type : Journal

Research teams : Milwaukee - Medical College of Wisconsin, Department of Surgery
Authors : Quebbeman EJ, Hamid AAR, Hoffman NE, Ausman RK.
Title : Stability of fluorouracil in plastic containers used for continuous infusion at home.
Reference : Am J Hosp Pharm ; 41: 1153-1156. 1984

Level of Evidence : 
Level of evidence D
Physical stability : 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Imperfect separation of the internal standard from the product under study or its degradation products, or understudied
No visual inspection
Degradation products not observed in real conditions

List of drugs
InjectionFluorouracil Anticancer drug
Stability in solutions Polyvinyl chloride Glucose 5% 10 mg/ml 25°C Light
112 Day
Stability in solutions Polyvinyl chloride Glucose 5% 10 mg/ml 5°C Protect from light
112 Day
Stability in solutions Polyisoprene elastomer Glucose 5% 8,3 mg/ml 5°C Protect from light
112 Day

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